I think that yesterday may have been the most difficult.  It seems that my skin seems to burn around 1 to 2 hours after application.  It was particularly painful yesterday but when I put my mind on something else, it's okay. I was cooking dinner last night and thought the steam and heat would be the end of me, but it actually subsided after concentrating on it.
I found sitting with the fan gently blowing on my face a great relief.

By night time the pain is completely gone.  Interestingly when we sleep our skin rejuvenates, apparently. My skin was constantly weeping.
This morning I applied my last dose of Picato.  It feels like I'm applying it to scales. I feel like I've got a facial mask on, if I smile hard, my skin craps (and weeps a little).
I'm not sure that glasses on my nose is ideal or if it is inhibiting the work, however, I am blind without them.

So, I am hopeful that from this point forward you will be see the regeneration of my new skin, cancer free.